International Congress on Science, Technology and Technology-based Innovation (STT), originally named “The Congress on Science and Technology of Thailand” with the same abbreviation of STT, is one of the most important scientific meetings in Thailand. It was firstly organized in 1974 by the Science Society of Thailand (SST) and Chulalongkorn University. Since then, the alternative Universities in Thailand have gone through the bidding for co-organizing the STT in the following years. It is the annual national congress for 45 years. To mark the 72nd Anniversary of the Science Society of Thailand in 2020, the congress has been changed to the international meeting. The aim is to create scientific forum for national and international scientists and technologists as well as young Thai scientists from diversified fields of science and technology to meet and to provide them the opportunity to share and exchange their knowledge and experiences. It is our annual congress, which originally was the national meeting since 1971, but this year, it is its first time to be held as the international meeting. Typically, the Congress Plenary Lecture is given by a Nobel Laureate in Science and Technology, followed by an honorable lecture of the Outstanding Scientist of Thailand in that particular year. During the Congress, lectures by several renowned invited speakers, panel discussions and hundreds of contributed papers from various areas of Science and Technology are presented orally or in the form of posters. In addition, the outstanding teacher awards, the young scientist awards, as well as the innovation awards and a display of national winners of high school student science projects are presented in the Congress. An exhibition of advanced scientific and technological instruments and appliances from suppliers and enterprises are also the attractive event of the Congress.